Laboratory reports are available for selected lots. Check each report for its result and stated method.
Kisspeptin-10
≥98% Purity
Class-level spec; selected lots third-party tested
COA Available
Batch report on request · HPLC identity check
Size
10mg
= Lab report published
€39.99
1
Total: €39.99
Free shipping on orders over €200
- If a product does not match the specification on its published COA, contact us with your batch number: we investigate against the lot report and replace any product that fails it, at no cost to you.
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3–7 days most of the EU · 10–14 Nordics/Baltics
Standard EU from €4.99 · core EU GLS €17.99 · Dispatched within 1–2 business days · Free shipping over €200 · no customs paperwork (EU).
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Research-grade Kisspeptin-10 for laboratory research. For research purposes only. Not for human consumption.
Volume Pricing
Applied automatically at checkout
| Quantity | Price Each | Total | Savings |
|---|---|---|---|
| 1 unit | €39.99 | €39.99 | — |
| 3+ | €37.99 | €113.97 | 5% off |
| 5+ Most Popular | €35.99 | €179.96 | 10% off |
| 10+ | €33.99 | €339.92 | 15% off |
Class-level specification on record; independent testing on selected lots.
Dispatched within 1–2 business days, shipping from €4.99 in the EU.
Ships across the EU plus Switzerland and the UK where permitted.
Kisspeptin-10 peptide
Kisspeptin-10 is a short peptide used in laboratory and preclinical research to study regulation of the reproductive hormone axis, including GnRH and LH release. Common applications include investigation of puberty timing, fertility mechanisms, metabolic influences on reproduction, and kisspeptin receptor signaling. While clinical uses remain under study, research has potential to inform diagnostics and therapies for reproductive endocrine disorders.
What Is Kisspeptin-10?
Kisspeptin-10 (KP-10) is a synthetic decapeptide corresponding to the active C-terminal region of the KISS1 gene product. Its sequence is YNWNSFGLRF-NH₂, including an amidated terminal phenylalanine.
This bioactive member of the kisspeptin family activates KISS1R, also called GPR54, a G-protein-coupled receptor involved in reproductive signalling. The receptor and its ligand are distinct molecules and should be identified correctly when selecting experimental materials.
| Characteristic | Detail |
|---|---|
| Sequence | YNWNSFGLRF-NH₂ |
| Molecular formula | C₆₃H₈₃N₁₇O₁₄ |
| Molecular weight | Approximately 1302.5 g/mol |
| Stated pack quantity | 10mg |
Scientific Background
The metastasis suppressor gene KiSS-1 encodes a precursor from which several related peptides are produced. Work by Kotani and colleagues helped identify these molecules as natural ligands for GPR54, connecting earlier melanoma research with receptor pharmacology.
Evidence about the precursor, longer peptides and KP-10 should be distinguished carefully. A result obtained with one KISS1-derived preparation does not automatically apply to every related sequence or commercial product.
Research Applications
Kisspeptin-10’s role in the hypothalamic-pituitary-gonadal axis makes it relevant to studies of gonadotropin-releasing hormone signalling. Investigations of this pathway have contributed to understanding reproductive development and puberty. The HPG axis provides a biological framework, but an isolated-cell experiment examines only selected parts of that system.
| Application | Experimental consideration |
|---|---|
| Receptor activation | Distinguish binding from downstream responses |
| Neuroendocrine signalling | Select endpoints appropriate to the model |
| Structure–function comparisons | Account for sequence and terminal modifications |
| In-vitro assays | Include suitable controls and concentration ranges |
Researchers may transfect CHO cells with a receptor construct to investigate signalling in a defined system. Expression levels and cell background can influence the results, so these conditions should be recorded alongside exposure time and assay methods.
Cell Migration and Tumour-Related Studies
Separate experiments have examined KP-10 as an inhibitor of angiogenesis-associated processes. Published work reported effects on endothelial cell migration, invasion and tube formation under specified conditions. These findings support further investigation rather than establishing an anticancer treatment.
Use in research should distinguish cell movement from changes in survival or proliferation. For example, a Cell Counting Kit-8 assay provides a metabolic viability readout; it does not directly measure migration. Complementary methods help researchers interpret whether an observed response reflects the mechanism being investigated.
Quality and Analytical Documentation
When selecting high-purity material, request the batch-specific certificate of analysis. Review the reported purity together with identity evidence, such as mass spectrometry, and check that the records match the supplied product.
Purity alone does not establish peptide quantity, sterility or biological activity. Preparation conditions and appropriate controls remain essential in research settings.
Preparation and Storage
The product is supplied as a lyophilised powder. Follow its documented solvent and handling instructions rather than assuming that one preparation method suits every assay.
If the supplier specifies that the material should be stored at -20°C, maintain those conditions and protect it from unsuitable light and moisture exposure. Where instructed, allow the sealed container to reach room temperature before opening to limit condensation.
Prepared solutions require their own validated storage limits. Use suitable aliquots to avoid repeated freeze-thaw cycles where the protocol recommends this. A clear solution does not confirm purity, sterility or successful preservation of activity.
The supplied reagent is not intended for use in humans or animals. Its research designation should not be presented as evidence of MHRA approval or suitability for clinical treatment.
Related studies:
Product Specifications
- Form: Lyophilized powder
- Purity: ≥98% (class-level specification)
- Storage: −20°C, protected from light
- Intended use: Laboratory research only
- Documentation: Batch certificate of analysis on request
COA Analysis
Selected lots are independently tested. Request the certificate for your batch number before the material enters an assay. Identity should match the stated sequence on the vial label.
For research purposes only. Not for human consumption.
Handling & Storage
Check the lot number against the certificate before the material enters an assay. Reconstitute only when the protocol calls for a working solution, using the solvent and concentration that protocol specifies. A prepared solution is not assumed to have the same storage life as the dry vial.
Store sealed vials at −20°C, protected from light and moisture. For research use only. Not for human or animal administration.
